To me, if you're going to add the superlative "biggest" to the bust term, you have to be talking about guys that were taken in the first half of the first round, if not the top ten. The hit rate for first round picks is about 50% so taking a guy like Paxton Lynch with the 26th pick, while still a bust, isn't going to make my list of biggest busts, because his draft position was probably inflated due to his position as a QB. He was a risk from the beginning, is what I'm saying. And putting him on the list with a guy like Josh Rosen isn't really fair, because Rosen was considered much more of a sure thing.
To me, in the last 10 years, it's guys like
Rosen
Sam Darnold
Clelin Ferrell
Morris Claiborne
Dion Jordan
Others to be sure, but those guys stick out to me