| Date | Time | Opponent | Location | Score | Media |
|---|---|---|---|---|---|
| Nov. 7 | 7:00 p.m. | IUPUI | Hilton Coliseum | 88-39, W | ESPN+ |
| Nov. 13 | 12:00 p.m. | North Carolina A&T | Hilton Coliseum | ESPN+ | |
| Nov. 20 | 5:00 p.m. | Milwaukee | Hilton Coliseum | ESPN+ | |
| Nov. 24 | 2:30 p.m. | Villanova (Phil Knight Inv.) | Portland, Oregon | ESPN2 | |
| Nov. 25 | TBD | UNC or Portland (Phil Knight Inv.) | Portland, Oregon | TBD | |
| Nov. 27 | TBD | Phil Knight Inv. Day 3 | Portland, Oregon | TBD | |
| Nov. 30 | 7:00 p.m. | North Dakota | Hilton Coliseum | ESPN+ | |
| Dec. 4 | 2:00 p.m. | St. John's | Hilton Coliseum | ESPN2 | |
| Dec. 8 | 7:00 p.m. | @ Iowa | Iowa City, Iowa | FS1 | |
| Dec. 11 | 5:00 p.m. | McNeese State | Hilton Coliseum | ESPN+ | |
| Dec. 18 | 12:00 p.m. | Western Michigan | Hilton Coliseum | ESPN+ | |
| Dec. 21 | 6:00 p.m. | Omaha | Hilton Coliseum | ESPN+ | |
| Dec. 31 | TBA | Baylor | Hilton Coliseum | ESPN2/U | |
| Jan. 4 | 6:00 p.m. | @ Oklahoma | Norman, Okla. | ESPN2/U | |
| Jan. 7 | 1:00 p.m. | @ TCU | Fort Worth, Texas | ESPNU | |
| Jan. 10 | 7:00 p.m. | Texas Tech | Hilton Coliseum | ESPN+ | |
| Jan. 14 | 3:00 p.m. | @ Kansas | Lawrence, Kan. | ESPN+ | |
| Jan. 17 | 7:00 p.m. | Texas | Hilton Coliseum | ESPN+ | |
| Jan. 21 | 1:00 p.m. | @ Oklahoma State | Stillwater, Okla. | ESPN+ | |
| Jan. 24 | 8:00 p.m. | Kansas State | Hilton Coliseum | ESPNU | |
| Jan. 28 | 1:00 p.m. | @ Missouri | Columbia, Missouri | ESPN/2/U | |
| Jan. 30 | 8:00 p.m. | @ Texas Tech | Lubbock, Texas | ESPN/2 | |
| Feb. 4 | 11:00 a.m. | Kansas | Hilton Coliseum | ESPN/2 | |
| Feb. 8 | 6:00 p.m. | @ West Virginia | Morgantown, W.V. | ESPN2/U | |
| Feb. 11 | 5:00 p.m. | Oklahoma State | Hilton Coliseum | ESPN2/U | |
| Feb. 15 | 8:00 p.m. | TCU | Hilton Coliseum | ESPN2/U | |
| Feb. 18 | 5:00 p.m. | @ Kansas State | Manhattan, Kan. | ESPN2/U | |
| Feb. 21 | 6:00 p.m. | @ Texas | Austin, Texas | LHN | |
| Feb. 25 | 11:00 a.m. | Oklahoma | Hilton Coliseum | ESPN2/U | |
| Feb. 27 | 8:00 p.m. | West Virginia | Hilton Coliseum | ESPN/2 | |
| Mar. 4 | 11 a.m. / 1 p.m. | @ Baylor | Waco, Texas | ESPN/2 | |
| Mar. 8-11 | TBA | Big 12 Tournament | Kansas City, Mo. | TBA |