| Date | Time | Opponent | Location | Score | Media/W-L |
|---|---|---|---|---|---|
| Nov. 4 | 7:00 p.m. | Mississippi Valley State (Stripe Hilton) | Hilton Coliseum | W, 83-44 | 1-0 (0-0) |
| Nov. 11 | 7:00 p.m. | Kansas City | Hilton Coliseum | W, 82-56 | 2-0 (0-0) |
| Nov. 12 | 7:00 p.m. | IU Indianapolis | Hilton Coliseum | W, 87-52 | 3-0 (0-0) |
| Nov. 25 | 8:00 p.m. | No. 4 Auburn (Maui Invitational) | Maui, Hawai'i | L, 83-81 | 3-1 (0-0) |
| Nov. 26 | 3:30 or 10 p.m. | Dayton/ (Maui Invitational) | Maui, Hawai'i | W, 89-84 | 4-1 (0-0) |
| Nov. 27 | TBD | Colorado (Maui Invitational) | Maui, Hawai'i | W, 99-71 | 5-1 (0-0) |
| Dec. 4 | 7:00 p.m. | No. 5 Marquette (Big East/Big 12 Battle) (White-Out) | Hilton Coliseum | W, 81-70 | 6-1 (0-0) |
| Dec. 8 | 5:00 p.m. | Jackson State | Hilton Coliseum | W, 100-58 | 7-1 (0-0) |
| Dec. 12 | 6:30 p.m. | @ Iowa | Iowa City, Iowa | W, 89-80 | 8-1 (0-0) |
| Dec. 15 | 12:00 p.m. | Omaha | Hilton Coliseum | W, 83-51 | 9-1 (0-0) |
| Dec. 22 | 12:00 p.m. | Morgan State | Hilton Coliseum | W, 99-72 | 10-1 (0-0) |
| Dec. 30 | 8:00 p.m. | Colorado | Boulder, Colo. | W, 79-69 | 11-1 (1-0) |
| Jan. 4 | 1:00 p.m. | No. 25 Baylor ('99-'00 & '00-'01 team recognition) | Hilton Coliseum | W, 74-55 | 12-1 (2-0) |
| Jan. 7 | 7:00 p.m. | Utah | Hilton Coliseum | W, 82-59 | 13-1 (3-0) |
| Jan. 11 | 1:00 p.m. | Texas Tech | Lubbock, Tex. | ESPN/ESPN2 | |
| Jan. 15 | 6:00 p.m. | Kansas | Hilton Coliseum | ESPN2 | |
| Jan. 18 | 4:00 p.m. | @ West Virginia | Morgantown, W.V. | ESPN+ | |
| Jan. 21 | 7:00 p.m. | UCF | Hilton Coliseum | ESPN+ | |
| Jan. 25 | 1:00 p.m. | @ Arizona State | Tempe, Ariz. | ESPN+ | |
| Jan. 27 | 9:30 p.m. | @ Arizona | Tucson, Ariz. | ESPN | |
| Feb. 1 | 1:00 p.m. | Kansas State (White-out) | Hilton Coliseum | ESPN/ESPN2 | |
| Feb. 3 | 8:00 p.m. | @ Kansas | Lawrence, Kan. | ESPN | |
| Feb. 8 | 12:00 p.m. | TCU | Hilton Coliseum | ESPN+ | |
| Feb. 11 | 6:00 p.m. | @ UCF | Orlando, Fla. | ESPN+ | |
| Feb. 15 | 3:00 p.m. | Cincinnati | Hilton Coliseum | ESPN/ESPN2 | |
| Feb. 18 | 7:00 p.m. | Colorado | Hilton Coliseum | ESPN+ | |
| Feb. 22 | 1:00 p.m. | @ Houston | Houston, Tex. | ESPN/ESPN2 | |
| Feb. 25 | 7:00 p.m. | @ Oklahoma State | Stillwater, OK | ESPN+ | |
| Mar. 1 | 8:00 p.m. | Arizona | Hilton Coliseum | ESPN | |
| Mar. 4 | 8:00 p.m. | BYU (Stripe Hilton) | Hilton Coliseum | ESPN/2/U | |
| Mar. 8 | 12:30 p.m. | @ Kansas State | Manhattan, Kan. | CBS | |
| Mar. 11-15 | TBA | Big 12 Tournament | Kansas City, Mo. | TBA |