On the defense side, the crazy thing for me is that ISU had six (seven according to the box score) sacks, and still gave up 500 yards of offense....that's kind of high. And yes, a bunch of it came on the last drive, but even considering that, ISU gave up over 400 yards before that last drive. It could have been big trouble if Duggan had played all game.
Regarding the running game, we'll find out soon enough. I expect the same treatment that ISU has received in the past, where the opponent is going to stuff the line/box and force ISU to make some passing plays.