I used to fly to visit mom and dad. Took me a day in airports. I could drive and be there for lunch the next day if I got on the road first thing in the morning. That was a no brainer. All day in my vehicle or all day in airports/airplanes. I'll pick my vehicle all day every day
12 seems way too high for this but it depends on lots of factors including how far you are from the departure airport, how far your destination is from the arrival airport, whether you'd need a layover, what time you want to leave/want to get there, etc.
It's "only" 11 hours (without stops) to drive from DSM to DFW. I'm flying that 10 out of 10 times.
Lots of factors, for sure. I also consider time of day that flight leaves, etc. Group vs. Solo travel, etc. Where you're going one you land, etc.
I flew solo from DSM to St. Louis twice on Southwest (direct flight) b/c it leaves early in the AM. Wake up at 4, leave around 5:30, at airport by 6, in the air by 7:20. Land shortly after 8, got my rental car and on the road before 9. Have the entire day that way.
I know some might say "but you can drive from Ankeny to St. Louis in 5 1/2 hours!" - I have to stop and pee every 2 hours so more like 6 1/2 for me. Plus @ airport, I can work on my laptop, and I can read in the air, etc. I don't like driving before daylight. I have lounge access so get a free breakfast in STL. I feel a LOT more fresh than starting a drive at 5:30 and driving until noon straight.
Similar to Pittsburgh once. Arrive around noon vs. an entire day of driving and exhaustion. My time off is the most valuable thing.
But I can completely respect people who prefer to drive, too. And flying with little kids is a pain, too. Just a lot of factors.