This is tough to judge because so much is new.
Both schools have graduated their best RB.
I understand UNI to be strong on defense - especially pass protection, so I don't see a lot of receiving yards for Cy.
If no RB for ISU steps up and does some damage, it will be a long night for the Cyclones.
The RBs for UNI, I think, are pretty strong, but not quite as strong as 2 years ago.
UNI has a new OC with a whole new system. And the QB race wasn't settled last I saw. If the starting QB doesn't run the system well and connect with receivers, it will be a long night for the Panthers with the defense on the field a lot.
If the ISU O-line can overwhelm the UNI D-line, ISU can win. But I don't see a lot of confidence out of ISU fans about the O-line.
UNI 24
ISU 14
But, as I said, so much is new this year for both teams, nothing would surprise me.