All it refers to is the fact that the majority of teams run a set play offense (like UNI) or a high post offense (like Creighton) or some other variation that utilizes a lot of clock, does not try to create early offense or fast break and relies on the half court to create scoring.
Teams in other conferences are more like to run a motion offense (Memphis, Kansas, Gonzaga) a dribble drive offense (Providence, Kentucky) a swing (Maryland, Wisconsin) or one of a hundred different systems. There are teams that run set play offenses like UNI - Michigan State being the prime example.
That is how I would consider the MVC different. However, I don't know how you can say the MVC style of play will work in any conference if you personally can't define it.
I don't think style of play is what differs between the high majors and the mid majors.
What differs is the type of players that you see...the typical player at the high major level tends to be much more athletic and much longer than you see at the mid major level.