I doubt if this is what you are asking, BUT. I would invest the most in the overhead compatible selection in whatever line you use. Wife and I have a set of decent Samsonite that we got on a trip to San Diego 25 years ago. I know the largest one of the group has been out of the house 6 or 7 times and that is because this is our 4th house. The carry on piece has been everywhere and easily over 250 "trips" (not vacation like trips).
Not a lot of help, but consider that.
Now that I'm thinking about it, you might have more years under your belt, so you already know what you use the most. Maybe a younger couple will read this and benefit. ha!