If I were to bet anything on this game I would say bet the over. I can see our defense struggling with their offense a little, and our offense practices against a better version of their defense every single day.
Unless something has changed, 1st/2nd team O and D don't face one another in practice during the season outside of camp scrimmages, maybe bye weeks.
Unless you're saying ISU's scout team D is better than Cincy's which would be pretty awesome.