Probably depends on the circumstances, but I don't know if I would.
Let's say (for the sake of argument) that Texas, Tech, OU, and OSU are headed to the Pac to create a Pac-16.
Our best-case scenario is probably for the other 6 schools to stick together and peel off some others to start a new conference, but I'm not sure about the likelihood of that. Kansas would be attractive to the Big Ten, and West Virginia may also be to the ACC.
Kansas and UConn could be #15 and #16 for the Big Ten. West Virginia and another of the AAC schools could be the same for the ACC.
ISU, KSU, BU, and TCU might end up in a 16-team AAC, playing the likes of SMU, Memphis, East Carolina, etc. in conference games. Or, if we could pull it off, we could just pick the 8 best schools out of the AAC and destroy that conference while still making our own. But we may lack the leverage to pull that off.
Of course - all speculation - thank God it won't come to that. (Hopefully.)