My 3 predictions. The last two can not both happen however.
#1: The lottery ticket wins and it is exactly $737,000 the exact amount of money he said he needed before he was done (Season 2)
#2: Saul confesses to Jesse that Walt killed Brock and Mike. Jesse teams up with Hank to get Walt.
#3: Hank will waltz in, sit down, and give a very casual "Hello, Jesse". Hank will throw out some more names, call him a piece of ****, and tell him he has a chance to redeem himself. That he's on the verge of catching Heisenberg, and all he needs is Jesse's confession to knowing something.
Here's where it'll fall apart: Hank will tell Jesse that if he gives him some solid evidence, Heisenberg will go down forever and Jesse will have a deal to be let free. Hank will offer a deal to work with Jesse in order to make sure he gets minimal sentencing, and Heisenberg will get everything that's coming to him. Now, Jesse is looking for punishment. He's looking to pay for the things he's done, so that deal doesn't work for him. Jesse looks up and says "I'm Heisenberg".