Ozempic, GLP-1 and other modern diabetes / weight loss medications

I take Mounjaro. Not for weight loss, but as a diabetic medication. It has been a game changer for me for my A1C and blood sugar levels. I admit I was a bit overweight, not fat by any means, and it has also helped with weight loss. I've dropped 35 pounds. The key though, is you have to change your life style. You can't just take the shot and then go eat a bag of oreos and sit on the couch. I cut back on my portions (a huge deal for me), cut out virtually all sweets/candy/desserts. I also stopped snacking in the evenings - in fact I almost never snack now. And I get as much protein as I can - high protein yogurts with breakfast, high protein virtually zero sugar/carb protein shakes, and I put flavorless protein powder in my morning tea. I am probably the healthiest I have been in my adult life. The Mounjaro was a big factor, no doubt. But you also have to have the will to change your lifestyle. My hope is that I can get off the medication at some point and because my lifestyle has changed, won't need it.
Can you share what the flavorless protein powder is? Whey or egg white powder?
 
I think the pill (orforglipron) is only a GLP-1 agonist, vs tirzepatide being a dual glp-1\GIP agonist, so effectiveness may be a bit different there.

Did you try reducing dose for a bit? (Or what dose did you end up on?)
I was at 10mg, but I was actually sharing a prescription of monjauro with my diabetic friend since my insurance wouldn't cover it and the medicine is too expensive for me, so I was taking it every other week. It was really working great with limited side effects at 10mg. I just stopped because I started getting too "sick" on day 3 each time. And then I took a long trip out of the country and didn't want to deal with it while traveling, and now just can't get myself to try it again.

Mostly, I just want something to help with the food noise and such. My eating habits have changed and I'm keeping the weight off without it, but I have a long ways to go, and I can feel the food noise becoming a problem again.

It really sucks that my insurance won't cover it. I even talked to my employer, and they said that adding it to the medical insurance plan is cost prohibitive (I think they're being ridiculous).
 
I was at 10mg, but I was actually sharing a prescription of monjauro with my diabetic friend since my insurance wouldn't cover it and the medicine is too expensive for me, so I was taking it every other week. It was really working great with limited side effects at 10mg. I just stopped because I started getting too "sick" on day 3 each time. And then I took a long trip out of the country and didn't want to deal with it while traveling, and now just can't get myself to try it again.

Mostly, I just want something to help with the food noise and such. My eating habits have changed and I'm keeping the weight off without it, but I have a long ways to go, and I can feel the food noise becoming a problem again.

It really sucks that my insurance won't cover it. I even talked to my employer, and they said that adding it to the medical insurance plan is cost prohibitive (I think they're being ridiculous).
Yeah if they just made something to help with food noise that would be amazing.
 
Late to the party/discussion on this...

Been on Ozempic for 1 year as a treatment for Type 2 diabetes. Results have been very positive with little to no side effects other than weight loss.

My A1c went from 7.3 -> 5.7 in about 3 months. Also dropped about 20lbs I could also see significant trend results in my CGM glucose measurements. Spikes from eating (low carb/zero sugar foods) were less pronounced.

I had been on Metformin and it didn't do much and created massive stomach issues for me. I'm also an avid bicyclist and could easily ride 100 miles so diet and exercise were already in place.

I've also been labeled the skinniest type 2 diabetic by those who know me (nickname aside). Full disclosure the bigbake nickname was more of an ironic twist on my skinny/height challenged me in high school.
 
I was at 10mg, but I was actually sharing a prescription of monjauro with my diabetic friend since my insurance wouldn't cover it and the medicine is too expensive for me, so I was taking it every other week. It was really working great with limited side effects at 10mg. I just stopped because I started getting too "sick" on day 3 each time. And then I took a long trip out of the country and didn't want to deal with it while traveling, and now just can't get myself to try it again.

Mostly, I just want something to help with the food noise and such. My eating habits have changed and I'm keeping the weight off without it, but I have a long ways to go, and I can feel the food noise becoming a problem again.

It really sucks that my insurance won't cover it. I even talked to my employer, and they said that adding it to the medical insurance plan is cost prohibitive (I think they're being ridiculous).

Wouldnt surprise me if it was the biweekly schedule. This leads to greater spikes and troughs in the concentration in your blood, likely peaking a couple days into each dose (where you saw the most sides). There can be benefits to those spikes for appetite suppression, but also seems to be where side effects can manifest. Different people seem to benefit from different schedules.

I know some people have gone the opposite direction when side effects have been too much, splitting their dose and doing it twice a week. That might be worth trying if you decide to get back onto it (easing your way back on over time as its all out of your system now)
 
Wouldnt surprise me if it was the biweekly schedule. This leads to greater spikes and troughs in the concentration in your blood, likely peaking a couple days into each dose (where you saw the most sides). There can be benefits to those spikes for appetite suppression, but also seems to be where side effects can manifest. Different people seem to benefit from different schedules.

I know some people have gone the opposite direction when side effects have been too much, splitting their dose and doing it twice a week. That might be worth trying if you decide to get back onto it (easing your way back on over time as its all out of your system now)
I hadn't considered that. Thanks.
 
Can you share what the flavorless protein powder is? Whey or egg white powder?
Sure. I use Vital Proteins, Collagen Peptides. I get the jugs at Costco. I typically put a half serving (2tbsp, 9g protein) in my tea and then add more when I make soups, etc. I wait until they have them on sale - which they seem to do every couple months and then buy a couple jugs.


I also recommend the Oikos Triple Zero yogurt. Good flavor and great for you. Also get these at Costco - WAY cheaper than at the grocery store.

 
  • Like
Reactions: hiltonisheaven
Sure. I use Vital Proteins, Collagen Peptides. I get the jugs at Costco. I typically put a half serving (2tbsp, 9g protein) in my tea and then add more when I make soups, etc. I wait until they have them on sale - which they seem to do every couple months and then buy a couple jugs.


I also recommend the Oikos Triple Zero yogurt. Good flavor and great for you. Also get these at Costco - WAY cheaper than at the grocery store.
+1 on the greek yogurt. Breakfast everyday for me, and sometimes an ice cream substitute after dinner.

But you have got to find the zero sugar ones (there are a few in addition ot the Oikos). <100 calories and 12-15g of protein. And usually taste decent, although I know some people can't stand the smell of greek yogurt.
 
  • Agree
Reactions: cyclones122
+1 on the greek yogurt. Breakfast everyday for me, and sometimes an ice cream substitute after dinner.

But you have got to find the zero sugar ones (there are a few in addition ot the Oikos). <100 calories and 12-15g of protein. And usually taste decent, although I know some people can't stand the smell of greek yogurt.
Totally agree. So many people eat yogurt thinking they are being healthy, but they are eating the wrong ones, which often are full of sugar and carbs. Same with "protein bars". Most of them are actually terrible for you.
 
  • Winner
Reactions: CascadeClone
Sure. I use Vital Proteins, Collagen Peptides. I get the jugs at Costco. I typically put a half serving (2tbsp, 9g protein) in my tea and then add more when I make soups, etc. I wait until they have them on sale - which they seem to do every couple months and then buy a couple jugs.


I also recommend the Oikos Triple Zero yogurt. Good flavor and great for you. Also get these at Costco - WAY cheaper than at the grocery store.


Ive seen where the collagen peptides don't help with muscle growth.

Not sure if that's true
 
Ive seen where the collagen peptides don't help with muscle growth.

Not sure if that's true
It’s more for skin/anti aging plus for joints but even then it’s more dubious how effective they are but since they have been a staple of many for a long time they are pretty safe so it’s not an issue
 
  • Like
Reactions: besserheimerphat
Totally agree. So many people eat yogurt thinking they are being healthy, but they are eating the wrong ones, which often are full of sugar and carbs. Same with "protein bars". Most of them are actually terrible for you.
It takes a little math but I always remind people there are 4 calories in a gram of protein, so if you add up a 30g protein bar or shake you get 120 calories. Compare that number yo the total calories and you can see just how much extra stuff was added
 
It takes a little math but I always remind people there are 4 calories in a gram of protein, so if you add up a 30g protein bar or shake you get 120 calories. Compare that number yo the total calories and you can see just how much extra stuff was added
Many supplement companies game the protein values by adding compounds heavy in nitrogen. The most basic protein tests are actually testing for nitrogen, which is a big component of protein. If the nutrition label people measure a lot of nitrogen, they assume most of it is protein and label it as such. The calorie check doesn't lie, and the calorie test isn't able to be gamed.

Protein = 4cal/g
Carb = 4cal/g
Fat = 9cal/g
Alcohol = 7cal/g

Do a sumproduct on the macros per serving and you should get almost exactly the stated calories per serving. If not, something is up.
 
For those jumping on the peptide train, there is a good review of the state of the industry by "Dr. Mike" Isreatel. Basically, only the GLP stuff has enough literature in human trials to show both safety and effectiveness. Everything else right now is a crapshoot. And he's not only a doctor, but also a bodybuilder who is very open about his past and current steroid use, and he's a proponent of using (proven) substances (responsibly and safely) to improve physique a d performance. If they worked, he'd be taking them himself.

 
It's a miracle drug. Heart disease, stroke, general inflammation all decrease with weight loss on top of all the other benefits. It is now being tested for helping gambling, nicotine and drug addiction.

They're already working on the next iterations of these drugs. Exciting times ahead.
We'll find out more if it really is a miracle or a curse. My wife's oncologist told us it was coming out in an oral version soon and will be widely and easily available.