Yeah, it seems like a good fit. If they're truly sold on Eli for the next couple years then they better surround him with some playmakers. Their receiving corps looks pretty well set. Add Barkley to the mix and there's a group that could prop Manning up.
I wouldn't normally hope for an RB that high but I think Saquon is a special talent that doesn't come around often. Another option I'd be fine with is taking Chubb or Nelson with the top pick and hoping Guice falls to them for their second pick but I wouldn't count on it.