Looking at their schedule, they'll likely sit him in one of these games:
Oral Roberts
North Florida
Cal Poly
ORU gave Okie St a good game - not a gimme for Iola.
N Fla lost to 15th ranked Florida by 15 and beat Florida National (?) and Ga Southern in close games.
Cal Poly has not won, but they played North Dak State tight (7 point loss) - Bison are probably on a similar talent level as Iowa.
If I had to guess, they'll sit him for N Fla or Cal Poly. If Fran was smart, he would play Jorbo in those games and sit him vs TTech. TTU's defense will eat his and Connor's breakfast, lunch and dinner. Might as well put him in the 3 winnable games before the difficult stretch leading up to their superbowl (Dec 12).