I'm from that area, worked downtown during my co-ops while I was in college and had a great time. If you can get an apartment close to downtown (if you are working in that area) with a patio, you are golden. Walking distance to the Old Market, which is a fun place during the evenings in the summer, but there are lots of other things to do too.
Casinos in Council Bluffs if you are in to that type of thing, plenty of fishing and outdoorsy things to do just outside of the city, lots of for fun sports leagues (sand volleyball, softball, etc).
It is probably as good as a place to be a young professional as Des Moines, you just trade hok fans for huskers.
Farnsworth and State43 are both in the Omaha area (farnsy will be away from the board for the next week or so). There are usually game watches at Fox and Hound bar out in West Omaha, which can be a fun place any night of the week.
As much as I rag on that area, there are much worse places to live.